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Da Vinci 32,Milano, Italy. Alighieri 11,Como, Italy. Sauro 17,Costamasnaga LCItaly. Correlating the features of the actual executed movement with the associated cortical activations fref enhance the reliability of the functional Magnetic Resonance Natching fMRI data interpretation.
This is crucial for longitudinal evaluation of motor recovery in neurological patients and for investigating detailed mutual interactions between activation maps and movement parameters.
Therefore, we have explored a new set-up combining fMRI with an optoelectronic motion capture system, which provides a multi-parameter quantification of the performed motor task.
The cameras of the motion system were mounted inside the MR room and passive markers were placed on the subject skin, without any risk or encumbrance. The versatile set-up allows 3-dimensional multi-segment acquisitions including recording of possible mirror movements, and it guarantees a high inter-sessions repeatability.
We demonstrated the integrated set-up reliability through compatibility tests. Then, an fMRI block-design protocol combined with kinematic recordings was tested on a healthy volunteer performing finger tapping and ankle dorsal- plantar-flexion. A preliminary assessment of clinical applicability and perspectives was carried out by pre- and post rehabilitation acquisitions on a hemiparetic patient performing ankle Private escort South Shields plantar-flexion.
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For all sessions, the proposed matvhing integrating kinematic data into the model design was compared with the standard analysis. Phantom acquisitions demonstrated the not-compromised image quality.
Healthy subject sessions showed the protocols feasibility and the model reliability with the kinematic regressor. The patient results showed that brain activation maps were more consistent when the images analysis included in the regression model, besides the stimuli, the kinematic regressor quantifying the actual executed movement movement timing and amplitudeproving a frse model improvement.
Moreover, concerning motor recovery evaluation, after one rehabilitation month, a greater cortical area was activated during exercise, in contrast to the usual focalization associated with functional recovery. Indeed, the availability of kinematics data allows to correlate this wider area with a higher frequency and a larger amplitude of movement.
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Functional magnetic resonance imaging fMRI is one of the main tools to investigate brain functional responses and follow-up their evolution. Its non-invasiveness, flexibility, spatial resolution, and reference to MRI anatomical images allows functional standard localizations. However, the analysis of fMRI performed during motor tasks in neurological patients affected by movement impairments e.
Indeed, the required task could be incorrectly carried out and involuntary movements could occur. Moreover, longitudinal studies require repeatability of motor tasks performed in matchung sessions, in order to not confuse changes in the execution of the movements with evolutions in the brain functional response.
Furthermore, mirror movements, i.
Several studies focusing on motor protocols under fMRI examination applied different methods to acquire movement performance outcomes.
Many fMRI studies used visual inspection [ 23 ], sometimes coupled to palpation [ 4 ], to evaluate subject's compliance to the requested Red latina Southampton obviously these methods are only qualitative.